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Analysis of microbial population genetic data

Niklaus J. Grünwald



Introduction

Analysis of population genetic data remains challenging. This site presents sample data, links and references to accompany my presentation given at a workshop that focused on the kinds of analyses typically done by plant pathologists and microbiologists. The workshop covered analyses of data from haploid and diploid populations with dominant or codominant marker systems applicable to a range of molecular genotyping techniques (including isozymes, AFLP, RFLP, RAPD, microsatellites and SNPs). The workshop included estimation of allele frequencies, inferences about Hardy-Weinberg and linkage disequilibrium, characterization of population structure, and estimation of population parameters such as mutation, recombination, and gene flow. More recent techniques in population genetic data analysis and parameter estimation, including coalescence, gene genealogies, and Bayesian analysis were introduced by Ignazio Carbone (see below). Participants received information to gain hands-on experience with various software packages for population genetic data using datasets provided at this website.

The workshop was held at the Annual Meeting of the American Phytopathological Society, Wednesday, August 3, 1:00 – 5:00 p.m., Austin, Texas.

For contributions by Ignazio Carbone please visit his website:

http://www.cals.ncsu.edu/plantpath/people/faculty/carbone/snap.html

 


Horticultural Crops Research Laboratory, USDA ARS
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E-mail: grunwaln@onid.orst.edu



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Last Updated: October 10, 2006