Research

The MFBS Center supports two research cores: the Carcinogenesis and Taxicogenomics Research Core and the Neuro and Developmental Toxicology Research Core.

The Carcinogenesis and Toxicogenomics Research Core utilizes both zebrafish and trout in studies that apply genomic approaches to ascertain mechanisms of action in neoplastic processes and possible pathways for inhibiting tumorigenesis.

The Neuro and Developmental Toxicology Research Core uses a number of in vitro (cell culture, fish chromatophores) and in vivo (zebrafish) models to address mechanisms of action of marine algae natural products and other chemicals toxic to the nervous system and/or to the developing embryo.

Facility Cores

Facility Cores provide specialized equipment and facilities, personnel, and expertise to support the research of investigators. The Marine and Freshwater Biomedical Sciences Center supports three Facility Cores:

The Aquatic Pathology Core provides high quality research animals (rainbow trout and zebrafish), exposure and rearing facilities, technical assistance, and specific expertise in surgery, necropsy, and histopathological evaluation in support of short-term and long-term research studies by Center Investigators.

Something's Fishy
This new mystery added to the Unsolved Mysteries web site focuses on developmental toxicology, zebrafish models, and an exciting new interactive animation showing the process of microarray technology. An interactive lab tour of the Tanguay facilities is also included in the Lab Tour section.

The Microarray Core provides guidance and software to aid in the selection and design of oligonucleotide probes, technical expertise and hardware for manufacturing custom arrays, preparation of samples, and analysis and graphical display of complex datasets.