Funding agency: 
National Science Foundationl

The unique environment on the ISS National Lab has many opportunities and can include high quality and long duration microgravity and extreme conditions including heat and cold cycling, high energy radiation, and vacuum. To receive funding as an NSF-ISS-appropriate project, a ISS-based flight experiment should be proposed. Selected projects must be flight ready within 18 months of the award and final reports must be completed by six months post-flight. If flight schedules change, investigators may modify proposed timelines, subject to review and approval by the CASIS Operations team. Prior to submitting a proposal to NSF, the Feasibility Review Form must be approved by CASIS.

Potential research may include areas such as (but not limited to)

  • Multiphase flow
  • Capillary flow
  • Separation/Agglomeration
  • Diffusion
  • Interfacial Behavior
  • Surface Tension
  • Biological and physiological transport

This Solicitation is not intended to be used for projects that can be accommodated within other NSF funding mechanisms. In addition, this Solicitation is not intended to be used for projects that can be conducted in their entirety with ground-based research.

Collaborative proposals can also be submitted. In these cases, if the PIs are at different institutions and have complementary skills and facilities, submission of separately submitted collaborative proposals is required. See PAPPG Chapter II.D.3.b for information about submission of a collaborative proposal from multiple organizations.

Prospective proposals will be subject to a review for operational feasibility and terrestrial benefit, both conducted by CASIS. See the CASIS guidelines for further details on these reviews at The solicitation seeks to increase use of the ISS National Lab for fluid dynamics and multiphase studies to benefit industries on Earth, to promote ISS as well as new & existing facility/technology utilization. Costs such as preparatory work, including but not limited to design of experimental prototypes and numerical simulations, data acquisition, and post-flight data analysis, can be included in the budget. CASIS can cover costs of modifications of flight equipment, if necessary. Ideal proposals will describe a commercial, civil, or academic project to achieve research or technology development objectives that will directly impact areas including (but not limited to):

  • Clean energy
  • Carbon emissions and capture
  • Manufacturing
  • Machinery
  • Consumer Products
  • Oil & Gas
  • Electronics
  • Medical Devices & Pharmaceuticals
  • Microfluidics

Prospective proposers should consult with the flight hardware directory on the CASIS website at as well as the Implementation Partner website page at to understand the basic capabilities of the ISS payload facilities and instrumentation. New hardware may also be proposed provided a design has been developed with an appropriate implementation partner. NSF will offer grants to research proposals that develop fundamental and translational research and CASIS will assist grantees in translating ground-based experiments and technologies into space-appropriate hardware where possible. An ideal proposal will demonstrate investigator's knowledge of the significant challenges and importance of the proposed research and how ISS utilization will allow their research goals to be achieved. All proposers should read this online material to clearly understand the hardware platform and capabilities on the ISS.

CASIS also encourages prospective proposers to learn about the availability and capability of flight hardware and integration services by directly communicating with the implementation partner and the CASIS Operations team ( Prospective proposers should read the CASIS guidelines at:

Proposals that do not follow the CASIS guidelines will be deemed non-responsive to this Solicitation.

March 5, 2018
Funding type: